HCID 21546866, compound → HCID 53828366, compound

HRID 1605554Notes

Reaction equation

HRID 1605554 reaction equation
C([NH:8]C1C=C(C=C(S(Cl)(=O)=O)C=1C1C=CC=CC=1)C(O)=O)C1C=CC=CC=1.Cl[S:29]([C:32]1[C:33]([C:45]2[CH:50]=[CH:49][CH:48]=[CH:47][CH:46]=2)=[C:34]([O:41][CH2:42][CH2:43][CH3:44])[CH:35]=[C:36]([CH:40]=1)[C:37]([OH:39])=[O:38])(=[O:31])=[O:30]>>[C:45]1([C:33]2[C:32]([S:29](=[O:31])(=[O:30])[NH2:8])=[CH:40][C:36]([C:37]([OH:39])=[O:38])=[CH:35][C:34]=2[O:41][CH2:42][CH2:43][CH3:44])[CH:50]=[CH:49][CH:48]=[CH:47][CH:46]=1

Participants

3

Reactant 2

HCID 21546866HCID 21546866, compoundHCID 21546869HCID 21546869, compound

Product 1

HCID 53828366HCID 53828366, compound

Procedure

By replacing in Example 1, step G, 3-benzylamino-5-chlorosulfonyl-4-phenylbenzoic acid with 5-chlorosulfonyl-4-phenyl-3-n-propoxybenzoic acid, and following the procedure described, 4-phenyl-3-n-propoxy-5-sulfamylbenzoic acid is obtained with a melting point of 155°-157° C.

Sources & evidence

ORD record
ord-14c62e3d7153434c9d85f3ad77485f83
Source dataset
uspto-grants-1976_04
Patent number
US03950380

Reaction notes

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