HCID 21546831, compound → HCID 21546827, compound

HRID 1605558Notes

Reaction equation

HRID 1605558 reaction equation
[CH2:1]([O:8][C:9]1[CH:10]=[C:11]([CH:15]=[C:16]([N+:24]([O-])=O)[C:17]=1[C:18]1[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=1)[C:12]([OH:14])=[O:13])[C:2]1C=CC=C[CH:3]=1.[N+](C1C(C2C=CC=CC=2)=C(OCC#C)C=C(C=1)C(O)=O)([O-])=O>>[NH2:24][C:16]1[C:17]([C:18]2[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=2)=[C:9]([O:8][CH2:1][C:2]#[CH:3])[CH:10]=[C:11]([CH:15]=1)[C:12]([OH:14])=[O:13]

Participants

3

Reactant 2

HCID 21546831HCID 21546831, compoundHCID 215468443-Benzyloxy-5-nitro-4-phenylbenzoic acid

Product 1

HCID 21546827HCID 21546827, compound

Procedure

By replacing in Example 2, step D, 3-benzyloxy-5-nitro-4-phenylbenzoic acid with 5-nitro-4-phenyl-3-propargyloxybenzoic acid, and following the procedure described, 5-amino-4-phenyl-3-propargyloxybenzoic acid is obtained with a melting point of 172°-173° C.

Sources & evidence

ORD record
ord-22a6fbafa7e44d0a9ae35677e709ba1f
Source dataset
uspto-grants-1976_04
Patent number
US03950380

Reaction notes

Loading…