HCID 21546817, compound → HCID 21546830, compound

HRID 1605561Notes

Reaction equation

HRID 1605561 reaction equation
C([NH:8]C1C=C(C=C(S(Cl)(=O)=O)C=1C1C=CC=CC=1)C(O)=O)C1C=CC=CC=1.Cl[S:29]([C:32]1[C:33]([C:48]2[CH:53]=[CH:52][CH:51]=[CH:50][CH:49]=2)=[C:34]([O:41][CH2:42][C:43]2[CH:47]=[CH:46][S:45][CH:44]=2)[CH:35]=[C:36]([CH:40]=1)[C:37]([OH:39])=[O:38])(=[O:31])=[O:30]>>[C:48]1([C:33]2[C:32]([S:29](=[O:31])(=[O:30])[NH2:8])=[CH:40][C:36]([C:37]([OH:39])=[O:38])=[CH:35][C:34]=2[O:41][CH2:42][C:43]2[CH:47]=[CH:46][S:45][CH:44]=2)[CH:53]=[CH:52][CH:51]=[CH:50][CH:49]=1

Participants

3

Reactant 2

HCID 21546817HCID 21546817, compoundHCID 21546866HCID 21546866, compound

Product 1

HCID 21546830HCID 21546830, compound

Procedure

By replacing in Example 1, step G, 3-benzylamino-5-chlorosulfonyl-4-phenylbenzoic acid with 5-chlorosulfonyl-4-phenyl-3-(3-thenyloxy)benzoic acid, and following the procedure described, 4-phenyl-5-sulfamyl-3-(3-thenyloxy)-benzoic acid is obtained with a melting point of 222°-223° C.

Sources & evidence

ORD record
ord-d3190a6ffaaa497ca5841e3e6f940845
Source dataset
uspto-grants-1976_04
Patent number
US03950380

Reaction notes

Loading…