HCID 21546866, compound → HCID 21546820, compound

HRID 1605567Notes

Reaction equation

C([NH:8]C1C=C(C=C(S(Cl)(=O)=O)C=1C1C=CC=CC=1)C(O)=O)C1C=CC=CC=1.Cl[S:29]([C:32]1[C:33]([C:47]2[CH:52]=[CH:51][CH:50]=[CH:49][CH:48]=2)=[C:34]([S:41][CH2:42][CH2:43][CH:44]([CH3:46])[CH3:45])[CH:35]=[C:36]([CH:40]=1)[C:37]([OH:39])=[O:38])(=[O:31])=[O:30]>>[CH2:42]([S:41][C:34]1[CH:35]=[C:36]([CH:40]=[C:32]([S:29](=[O:31])(=[O:30])[NH2:8])[C:33]=1[C:47]1[CH:52]=[CH:51][CH:50]=[CH:49][CH:48]=1)[C:37]([OH:39])=[O:38])[CH2:43][CH:44]([CH3:46])[CH3:45]

Participants

Reactant 2

HCID 21546866HCID 21546866, compound

HCID 21546890HCID 21546890, compound

Product 1

HCID 21546820HCID 21546820, compound

Procedure

By replacing in Example 1, step G, 3-benzylamino-5-chlorosulfonyl-4-phenylbenzoic acid with 5-chlorosulfonyl-3-isopentylthio-4-phenylbenzoic acid, and following the procedure described, 3-isopentylthio-4-phenyl-5-sulfamylbenzoic acid is obtained crystallizing with 0.5 mole of ethanol with a melting point of 70°-74° C.

Sources & evidence

ORD record: ord-44d27a02c07d4e048fdb7a6aaa7d71e4
Source dataset: uspto-grants-1976_04
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US03950380

Reaction notes

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