3-Benzyloxy-5-nitro-4-phenylbenzoic acid → 3-Allylthio-5-amino-4-phenylbenzoic acid

HRID 1605568Notes

Reaction equation

HRID 1605568 reaction equation
C(OC1C=C(C=C([N+]([O-])=O)C=1C1C=CC=CC=1)C(O)=O)C1C=CC=CC=1.[CH2:27]([S:30][C:31]1[CH:32]=[C:33]([CH:37]=[C:38]([N+:46]([O-])=O)[C:39]=1[C:40]1[CH:45]=[CH:44][CH:43]=[CH:42][CH:41]=1)[C:34]([OH:36])=[O:35])[CH:28]=[CH2:29]>>[CH2:27]([S:30][C:31]1[CH:32]=[C:33]([CH:37]=[C:38]([NH2:46])[C:39]=1[C:40]1[CH:45]=[CH:44][CH:43]=[CH:42][CH:41]=1)[C:34]([OH:36])=[O:35])[CH:28]=[CH2:29]

Participants

3

Reactant 2

HCID 215468443-Benzyloxy-5-nitro-4-phenylbenzoic acidHCID 215468723-Allylthio-5-nitro-4-phenylbenzoic acid

Product 1

HCID 215468983-Allylthio-5-amino-4-phenylbenzoic acid

Procedure

By replacing in Example 2, step D, 3-benzyloxy-5-nitro-4-phenylbenzoic acid with 3-allylthio-5-nitro-4-phenylbenzoic acid, and following the procedure described, 3-allylthio-5-amino-4-phenylbenzoic acid is obtained with a melting point of 149.5°-150.5° C.

Sources & evidence

ORD record
ord-49190698e1ef4e48a8b41080c3b47eee
Source dataset
uspto-grants-1976_04
Patent number
US03950380

Reaction notes

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