3-Benzyloxy-5-nitro-4-phenylbenzoic acid → 5-Amino-3-crotylthio-4-phenylbenzoic acid

HRID 1605570Notes

Reaction equation

HRID 1605570 reaction equation
C(OC1C=C(C=C([N+]([O-])=O)C=1C1C=CC=CC=1)C(O)=O)C1C=CC=CC=1.[CH2:27]([S:31][C:32]1[CH:33]=[C:34]([CH:38]=[C:39]([N+:47]([O-])=O)[C:40]=1[C:41]1[CH:46]=[CH:45][CH:44]=[CH:43][CH:42]=1)[C:35]([OH:37])=[O:36])[CH:28]=[CH:29][CH3:30]>>[NH2:47][C:39]1[C:40]([C:41]2[CH:42]=[CH:43][CH:44]=[CH:45][CH:46]=2)=[C:32]([S:31][CH2:27][CH:28]=[CH:29][CH3:30])[CH:33]=[C:34]([CH:38]=1)[C:35]([OH:37])=[O:36]

Participants

3

Reactant 2

HCID 215468443-Benzyloxy-5-nitro-4-phenylbenzoic acidHCID 538223533-Crotylthio-5-nitro-4-phenylbenzoic acid

Product 1

HCID 537737715-Amino-3-crotylthio-4-phenylbenzoic acid

Procedure

By replacing in Example 2, step D, 3-benzyloxy-5-nitro-4-phenylbenzoic acid with 3-crotylthio-5-nitro-4-phenylbenzoic acid, and following the procedure described, 5-amino-3-crotylthio-4-phenylbenzoic acid is obtained with a melting point of 102°-104° C.

Sources & evidence

ORD record
ord-aeb85b1ff4fa489f8a566657d8a5ac9f
Source dataset
uspto-grants-1976_04
Patent number
US03950380

Reaction notes

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