HCID 21546866, compound → HCID 54063665, compound

HRID 1605571Notes

Reaction equation

HRID 1605571 reaction equation
C([NH:8]C1C=C(C=C(S(Cl)(=O)=O)C=1C1C=CC=CC=1)C(O)=O)C1C=CC=CC=1.Cl[S:29]([C:32]1[C:33]([C:46]2[CH:51]=[CH:50][CH:49]=[CH:48][CH:47]=2)=[C:34]([S:41][CH2:42][CH:43]=[CH:44][CH3:45])[CH:35]=[C:36]([CH:40]=1)[C:37]([OH:39])=[O:38])(=[O:31])=[O:30]>>[CH2:42]([S:41][C:34]1[CH:35]=[C:36]([CH:40]=[C:32]([S:29](=[O:31])(=[O:30])[NH2:8])[C:33]=1[C:46]1[CH:51]=[CH:50][CH:49]=[CH:48][CH:47]=1)[C:37]([OH:39])=[O:38])[CH:43]=[CH:44][CH3:45]

Participants

3

Reactant 2

HCID 21546866HCID 21546866, compoundHCID 54083085HCID 54083085, compound

Product 1

HCID 54063665HCID 54063665, compound

Procedure

By replacing in Example 1, step G, 3-benzylamino-5-chlorosulfonyl-4-phenylbenzoic acid with 5-chlorosulfonyl-3-crotylthio-4-phenylbenzoic acid, and following the procedure described, 3-crotylthio-4-phenyl-5-sulfamylbenzoic acid is obtained crystallizing with 0.5 mole of ethanol with a melting point of 89°-91° C.

Sources & evidence

ORD record
ord-b0f8fd28111a4484a7e167604fafa470
Source dataset
uspto-grants-1976_04
Patent number
US03950380

Reaction notes

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