5-Chlorosulfonyl-3-nitro-4-phenylbenzoic acid → 3-Nitro-4-phenyl-5-sulfamylbenzoic acid

HRID 1605574Notes

Reaction equation

HRID 1605574 reaction equation
C([NH:8]C1C=C(C=C(S(Cl)(=O)=O)C=1C1C=CC=CC=1)C(O)=O)C1C=CC=CC=1.Cl[S:29]([C:32]1[C:33]([C:44]2[CH:49]=[CH:48][CH:47]=[CH:46][CH:45]=2)=[C:34]([N+:41]([O-:43])=[O:42])[CH:35]=[C:36]([CH:40]=1)[C:37]([OH:39])=[O:38])(=[O:31])=[O:30]>>[N+:41]([C:34]1[CH:35]=[C:36]([CH:40]=[C:32]([S:29](=[O:31])(=[O:30])[NH2:8])[C:33]=1[C:44]1[CH:49]=[CH:48][CH:47]=[CH:46][CH:45]=1)[C:37]([OH:39])=[O:38])([O-:43])=[O:42]

Participants

3

Reactant 2

HCID 215468625-Chlorosulfonyl-3-nitro-4-phenylbenzoic acidHCID 21546866HCID 21546866, compound

Product 1

HCID 215468433-Nitro-4-phenyl-5-sulfamylbenzoic acid

Procedure

By replacing in Example 1, step G, 3-benzylamino-5-chlorosulfonyl-4-phenylbenzoic acid with 5-chlorosulfonyl-3-nitro-4-phenylbenzoic acid, and following the procedure described, 3-nitro-4-phenyl-5-sulfamylbenzoic acid is obtained as a hydrate with a melting point of 119°-121° C.

Sources & evidence

ORD record
ord-f217a0ef0dd34aa58811f923c0aa3459
Source dataset
uspto-grants-1976_04
Patent number
US03950380

Reaction notes

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