3-Amino-5-nitro-4-phenylbenzoic acid → HCID 21546851, compound

HRID 1605576Notes

Reaction equation

HRID 1605576 reaction equation
N[C:2]1[CH:3]=[C:4]([CH:8]=[C:9]([N+]([O-])=O)[C:10]=1C1C=CC=CC=1)[C:5](O)=O.[NH2:20][C:21]1[CH:22]=[C:23]([CH:27]=[C:28]([S:36](=[O:39])(=[O:38])[NH2:37])[C:29]=1[C:30]1[CH:35]=[CH:34][CH:33]=[CH:32][CH:31]=1)[C:24]([OH:26])=[O:25]>>[CH2:5]([NH:20][C:21]1[CH:22]=[C:23]([CH:27]=[C:28]([S:36](=[O:39])(=[O:38])[NH2:37])[C:29]=1[C:30]1[CH:35]=[CH:34][CH:33]=[CH:32][CH:31]=1)[C:24]([OH:26])=[O:25])[C:4]1[CH:8]=[CH:9][CH:10]=[CH:2][CH:3]=1

Participants

3

Reactant 2

HCID 124087693-Amino-5-nitro-4-phenylbenzoic acidHCID 215468413-Amino-4-phenyl-5-sulfamylbenzoic acid

Product 1

HCID 21546851HCID 21546851, compound

Procedure

By replacing in Example 1, step D, 3-amino-5-nitro-4-phenylbenzoic acid with an equimolar amount of 3-amino-4-phenyl-5-sulfamylbenzoic acid, and following the procedure described, 3-benzylamino-4-phenyl-5-sulfamylbenzoic acid is obtained with a melting point of 221°-222° C. The material is identical (IR, analysis) with the material prepared as in Example 1, step G.

Sources & evidence

ORD record
ord-43952021a45144c4b8cff70b9a11bdec
Source dataset
uspto-grants-1976_04
Patent number
US03950380

Reaction notes

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