HCID 21547094, compound → HCID 21547157, compound

HRID 1605653Notes

Reaction equation

HRID 1605653 reaction equation
[Cl:1][C:2]1[CH:7]=[C:6]([CH2:8][CH2:9][C:10](=[O:12])[CH3:11])[CH:5]=[CH:4][C:3]=1[C:13]1[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=1>C1C=CC=CC=1.C(OCC)(=O)C>[Cl:1][C:2]1[CH:7]=[C:6]([CH2:8][CH2:9][CH:10]([OH:12])[CH3:11])[CH:5]=[CH:4][C:3]=1[C:13]1[CH:14]=[CH:15][CH:16]=[CH:17][CH:18]=1

Participants

3

Reactant 1

HCID 21547094HCID 21547094, compound

Product 1

HCID 21547157HCID 21547157, compoundYield 78%

Reagents, catalysts & solvents 1

HCID 21583983Benzene ethyl acetateSolvent

Procedure

4-(2-Chloro-4-biphenylyl)-2-butanol was prepared analogous to Example 26 from 4-(2-chloro-4-biphenylyl)-2-butanone with a yield of 78% of theory. The product was obtained as a colorless, viscous, non-crystallizing oil after chromatography on silicagel (Rf -value 0.60, prepared silicagel plates, thickness of layer 0.25 mm; benzene/ethyl acetate, ratio by volume 1:1, as eluant), which was characterized by IR-, UV-, NMR-spectra and by elementary analysis.

Workup

  1. customThe product was obtained as a colorless, viscous, non-crystallizing oil after chromatography

Sources & evidence

ORD record
ord-845f07121765431d86d3a28892d7f852
Source dataset
uspto-grants-1976_04
Patent number
US03950427

Reaction notes

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