HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethyl (2E)-3-ethoxy-2-butenoate → (E)-4-(3-Bromo-4-cyclohexyl-phenyl)-3-pentene-2-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethyl (2E)-3-ethoxy-2-butenoate | HCID 5354173 | — |
| Reactant | 3'-Bromo-4'-cyclohexylacetophenone | HCID 21547145 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | (E)-4-(3-Bromo-4-cyclohexyl-phenyl)-3-pentene-2-one | HCID 68134037 | 69% |
Reaction Steps
(E)-4-(3-Bromo-4-cyclohexyl-phenyl)-3-pentene-2-one was prepared analogous to Example 52, from 3'-bromo-4'-cyclohexylacetophenone (b.p. 135°-138°C at 0.15 mm Hg; nD20 = 1.5740) an ethyl (E)-3-ethoxy-crotonate with a yield of 69% of theory. B.p. 170°-175°C at 0.3 mm Hg; m.p. 52°-53°C (from methanol).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US03950427 |
| Source dataset | uspto-grants-1976_04 |
| ORD ID | ord-1a14c392d3e74f2d8a6712e9a443216e |
| Source note | uspto-grants-1976_04 |