HCID 21547130, compound → HCID 21547128, compound

HRID 1605669Notes

Reaction equation

HRID 1605669 reaction equation
[Cl:1][C:2]1[CH:3]=[C:4]([CH:14]([CH3:19])[CH2:15][C:16](N)=[O:17])[CH:5]=[CH:6][C:7]=1[CH:8]1[CH2:13][CH2:12][CH2:11][CH2:10][CH2:9]1.[CH3:20][Mg]Br>>[Cl:1][C:2]1[CH:3]=[C:4]([CH:14]([CH3:19])[CH2:15][C:16](=[O:17])[CH3:20])[CH:5]=[CH:6][C:7]=1[CH:8]1[CH2:13][CH2:12][CH2:11][CH2:10][CH2:9]1

Participants

3

Reactant 2

HCID 21547130HCID 21547130, compoundHCID 178418573HCID 178418573, compound

Product 1

HCID 21547128HCID 21547128, compoundYield 74%

Procedure

4-(3-Chloro-4-cyclohexyl-phenyl)-2-pentanone was prepared analogous to Example 61 from 3-(3-chloro-4-cyclohexyl-phenyl)-butyramide and methyl-magnesium bromide with a yield of 74% of theory. The colorless, highly viscous oil had a b.p. of 153°-156°C at 0.1 mm Hg.

Sources & evidence

ORD record
ord-144ec9e7930e49bc89e99a40bc0629ff
Source dataset
uspto-grants-1976_04
Patent number
US03950427

Reaction notes

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