Ethyl (2E)-3-ethoxy-2-butenoate → HCID 68135631, compound

HRID 1605674Notes

Reaction equation

HRID 1605674 reaction equation
[Cl:1][C:2]1[CH:3]=[C:4]([C:13](=O)[CH3:14])[CH:5]=[CH:6][C:7]=1[CH:8]1[CH2:12][CH2:11][CH2:10][CH2:9]1.C([O:18]/[C:19](/[CH3:26])=[CH:20]/C(OCC)=O)C>>[Cl:1][C:2]1[CH:3]=[C:4](/[C:13](/[CH3:14])=[CH:20]/[C:19](=[O:18])[CH3:26])[CH:5]=[CH:6][C:7]=1[CH:8]1[CH2:12][CH2:11][CH2:10][CH2:9]1

Participants

3

Reactant 2

HCID 5354173Ethyl (2E)-3-ethoxy-2-butenoateHCID 21547162HCID 21547162, compound

Product 1

HCID 68135631HCID 68135631, compoundYield 82%

Procedure

(E)-4-(3-chloro-4-cyclopentyl-phenyl)-3-pentene-2-one was prepared analogous to Example 52 from 3'-chloro-4'-cyclopentyl-acetophenone (b.p. 130°-135°C at 0.1 mm Hg) and ethyl (E)-3-ethoxy-crotonate with a yield of 82% of theory. B.p. 130°-135°C at 0.1 mm Hg.

Sources & evidence

ORD record
ord-d22b593f920945beb4ad6e81672dbbb7
Source dataset
uspto-grants-1976_04
Patent number
US03950427

Reaction notes

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