beta-Aminobeta-ethoxyacrylic acid ethyl ester → HCID 20367251, compound

HRID 1605714Notes

Reaction equation

HRID 1605714 reaction equation
C([O:3][C:4](=O)[CH:5]=[C:6]([NH2:10])OCC)C.[F:12][C:13]([F:25])([F:24])[O:14][C:15]1[CH:23]=[CH:22][C:18]([CH2:19][NH:20][NH2:21])=[CH:17][CH:16]=1>>[NH2:10][C:6]1[NH:21][N:20]([CH2:19][C:18]2[CH:22]=[CH:23][C:15]([O:14][C:13]([F:24])([F:25])[F:12])=[CH:16][CH:17]=2)[C:4](=[O:3])[CH:5]=1

Participants

3

Reactant 2

HCID 278451beta-Aminobeta-ethoxyacrylic acid ethyl esterHCID 20367188{[4-(Trifluoromethoxy)phenyl]methyl}hydrazine

Product 1

HCID 20367251HCID 20367251, compound

Procedure

From 17.5 g of β-amino-β-ethoxyacrylic acid ethyl ester and 20.6 g of 4-trifluoromethoxybenzylhydrazine, analogously to the procedure described in Example 1. 8.7 g of the compound identified above as colorless crystals of melting point 99°, corresponding to 32% of theory, are obtained.

Workup

  1. customare obtained

Sources & evidence

ORD record
ord-3b6049608a4f44c9a37ab6af9b3173eb
Source dataset
uspto-grants-1976_04
Patent number
US03950528

Reaction notes

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