HuagongsheHuagongshe Chemistry Print Report · For research reference only
p-Toluenesulfonic acid → HCID 20367252, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | p-Toluenesulfonic acid | HCID 6101 | — |
| Reactant | beta-Aminobeta-ethoxyacrylic acid ethyl ester | HCID 278451 | — |
| Reactant | {[2-(Trifluoromethyl)phenyl]methyl}hydrazine | HCID 20367279 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | HCID 20367252 | HCID 20367252 | — |
Reaction Steps
46 g of 2-trifluoromethylbenzylhydrazine were added dropwise, under nitrogen, to a solution of 38.2 g of β-amino-β-ethoxyacrylic acid ethyl ester and 2 g of p-toluenesulphonic acid in 250 ml of ethanol. After stirring overnight, the solvent was distilled off in vacuo and the residue was recrystallised from ethanol. The product was the compound identified above. Melting point: 184°, 22 g (34%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US03950528 |
| Source dataset | uspto-grants-1976_04 |
| ORD ID | ord-8b2ecded345d4c39bbbdabab3927873f |
| Source note | uspto-grants-1976_04 |