beta-Aminobeta-ethoxyacrylic acid ethyl ester → HCID 20367254, compound

HRID 1605736Notes

Reaction equation

HRID 1605736 reaction equation
C([O:3][C:4](=O)[CH:5]=[C:6]([NH2:10])OCC)C.[Cl:12][C:13]1[CH:14]=[C:15]([CH:19]=[CH:20][CH:21]=1)[CH2:16][NH:17][NH2:18]>C(O)C>[NH2:10][C:6]1[NH:18][N:17]([CH2:16][C:15]2[CH:19]=[CH:20][CH:21]=[C:13]([Cl:12])[CH:14]=2)[C:4](=[O:3])[CH:5]=1

Participants

4

Reactant 2

HCID 278451beta-Aminobeta-ethoxyacrylic acid ethyl esterHCID 7219929(3-chlorobenzyl)hydrazine

Product 1

HCID 20367254HCID 20367254, compoundYield 42%

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent2×

Procedure

35 g (10% excess) of β-amino-β-ethoxyacrylic acid ethyl ester are introduced into 100 ml of ethanol. 32 g of 3-chlorobenzylhydrazine in 50 ml of ethanol are added while stirring. The mixture is worked up as above. 18.9 g of the compound identified above, as colorless felted needles of melting point 132°, are obtained. (Yield: 42% of theory)

Workup

  1. customare obtained

Sources & evidence

ORD record
ord-0fa0aa4e0ed8410980b72ff3af47bde8
Source dataset
uspto-grants-1976_04
Patent number
US03950528

Reaction notes

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