Phenylacetaldehyde → 1,4-Anhydro-6-deoxy-1,4-dimethyl-6-phenylhex-1-en-3-ulose

Participants

Reaction Conditions

Reaction Steps

To a mixture of 6 g (0.05 mole) phenylacetaldehyde and 1.28 g (0.01 mole) of 2.5-dimethyl-4-hydroxy-3-(2H)-furanone was added 60 mg of boric acid and the mixture was stirred at 80°C for 3 hours. After working up the reaction mixture as described earlier, 0.57 g (23%) of the title compound was obtained, with melting point 157.5°-159°C.

Provenance & Evidence