Sodium Iodide → HCID 21545459, compound

Participants

Reaction Steps

The 1-p-Fluorobenzoyl-1-(alpha-naphthoxy)-3-chloropropane is prepared as follows. A solution of 20 g. of 1-p-fluorobenzoyl-1-bromo-3-chloropropane in 60 cc. anhydrous acetone is added slowly over half an hour while stirring to a suspension of 10.4 g. of α-naphthol, 0.72 g. of sodium iodide and 16.8 g. of K2CO3 in 300 cc. anhydrous acetone. When the addition is complete, the mixture is refluxed for 10 hours and then cooled. The solid therein is filtered off and the solvent is removed from the filtrate at reduced pressure. The residue melts at 147°C (from benzene).

Provenance & Evidence