Water → HCID 20355353, compound

HRID 1605919Notes

Reaction equation

HRID 1605919 reaction equation
[N+:1]([C:4]1[CH:19]=[CH:18][C:7]2[N:8]=[C:9](SC)[C:10]3[C:11](=[CH:13][S:14][CH:15]=3)[NH:12][C:6]=2[CH:5]=1)([O-:3])=[O:2].O.[CH2:21]([N:28]1[CH2:33][CH2:32][NH:31][CH2:30][CH2:29]1)[C:22]1[CH:27]=[CH:26][CH:25]=[CH:24][CH:23]=1>C(O)(=O)C>[N+:1]([C:4]1[CH:19]=[CH:18][C:7]2[N:8]=[C:9]([N:31]3[CH2:32][CH2:33][N:28]([CH2:21][C:22]4[CH:23]=[CH:24][CH:25]=[CH:26][CH:27]=4)[CH2:29][CH2:30]3)[C:10]3[C:11](=[CH:13][S:14][CH:15]=3)[NH:12][C:6]=2[CH:5]=1)([O-:3])=[O:2]

Participants

5

Reactant 3

HCID 962WaterHCID 759941-BenzylpiperazineHCID 20355322HCID 20355322, compound

Product 1

HCID 20355353HCID 20355353, compound

Reagents, catalysts & solvents 1

HCID 176Acetic AcidSolvent

Procedure

A solution of 6-nitro 10-(methylthio)-4H-thieno [3,4-b] [1,5] benzodiazepine in excess N-benzylpiperazine and glacial acetic acid is heated at 140°-160°C. for 2 days. The solution is poured into water and the product is collected.

Workup

  1. customthe product is collected

Sources & evidence

ORD record
ord-6bd5e0e08f8c4631b2f77c82aaafd33b
Source dataset
uspto-grants-1976_04
Patent number
US03951981

Reaction notes

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