HuagongsheHuagongshe Chemistry Print Report · For research reference only
Aldoxime → Acetonitrile oxide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Aldoxime | HCID 7863 | — |
| Reactant | Chlorine | HCID 24526 | — |
| Reactant | 2,3-Dichloro-1,4-benzoquinone | HCID 138423 | — |
| Reactant | Sodium Bicarbonate | HCID 516892 | — |
| Solvent | Water | HCID 962 | — |
| Product | Acetonitrile oxide | HCID 522391 | — |
| Product | HCID 21545721 | HCID 21545721 | — |
Reaction Steps
A solution of acetonitrile oxide was prepared by passing chlorine (10.8 grams) over 30 minutes into a stirred suspension of acetaldoxime (9 grams) and sodium bicarbonate (25.2 grams) in water at 0° C was added 2,3-dichlorobenzoquinone (17.7 grams) portionwise over 15 minutes. The mixture was stirred at 0°-5° C for 2 hours and then extracted with methylene chloride. The dried extracts were evaporated to dryness under reduced pressure and the residue recrystallized from ethanol to give the desired product as yellow crystals having a melting point of 214°-215° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US03952003 |
| Source dataset | uspto-grants-1976_04 |
| ORD ID | ord-a707d3f725624214a4ace320b4d506a7 |
| Source note | uspto-grants-1976_04 |