Tetrahydrofuran → 1-Diallylcarbamoyl-3-n-butylthio-1,2,4-triazole

Participants

Reaction Steps

A mixture of 6.3 g. 3-n-butylthio-1,2,4-triazole, 6.8 g. diallylcarbamoyl chloride, 25 ml. tetrahydrofuran and 8 ml. dry triethylamine was refluxed under anhydrous conditions for 4 hours. The reaction mixture was worked up as described in Example1 to produce an oil which was distilled under reduced pressure to give 1-diallylcarbamoyl-3-n-butylthio-1,2,4-triazole, b.p. 157°C./0.6 mm. (95.0% 1-isomer by GLC assay). Elemental analysis satisfactory.

Provenance & Evidence