Tetrahydrofuran → HCID 20354956, compound

Participants

Reaction Steps

A mixture of 5.75 g. 3-isopropylthio-1,2,4-triazole, 6.8 g. diallylcarbamoyl chloride, 25 ml. dry tetrahydrofuran and 8 ml. dry triethylamine was refluxed under anhydrous conditions for 2.5 hours. The reaction mixture was worked up as described in Example 1 to produce an oily residue which was distilled under reduced pressure to give 1-diallylcarbamoyl-3-isopropylthio-1,2,4-triazole, b.p. 133°C./0.4 mm. - 144°C./0.9 mm. (97.2% 1-isomer by GLC assay). Elemental analysis satisfactory.

Provenance & Evidence