Ethanol → HCID 23336681, compound

Participants

Reaction Steps

A solution of 10.6 parts of 6-hydroxy-1-thiachromone-2-carboxylic acid and 9 parts of concentrated sulphuric acid in 750 parts of ethanol was heated under reflux for 20 hours. Most of the ethanol was evaporated off and the residual solution was diluted with 500 parts of water, which caused precipitation of a solid. The solid was filtered off, washed with dilute sodium bicarbonate solution and with water and was finally crystallised from ethanol to give 9.4 parts of ethyl 6-hydroxy-1-thiachromone-2-carboxylate, melting point 217°-8°C.

Provenance & Evidence