HuagongsheHuagongshe Chemistry Print Report · For research reference only
3,4-Dichlorobenzyl chloride → 4-Methyl-1-(3,4-dichlorobenzyl)-pyrazol-5-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3,4-Dichlorobenzyl chloride | HCID 7609 | — |
| Reactant | Sodium hydride | HCID 24758 | — |
| Reactant | 4-Methylpyrazol-5-one | HCID 19926084 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | 4-Methyl-1-(3,4-dichlorobenzyl)-pyrazol-5-one | HCID 23334400 | — |
Reaction Steps
19.6 g of 4-methylpyrazol-5-one were added in portions to a suspension of 5.0 g of sodium hydride in 100 ml of absolute dimethylformamide. After the evolution of H2 had ceased, 39 g of 3,4-dichlorobenzyl chloride were added dropwise to the reaction solution.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US03952008 |
| Source dataset | uspto-grants-1976_04 |
| ORD ID | ord-8a53fbbda8704db79c01118842d7c88d |
| Source note | uspto-grants-1976_04 |