Piperidine-1-sulfonyl chloride → HCID 68147447, compound

HRID 1606301Notes

Reaction equation

HRID 1606301 reaction equation
[OH:1][C:2]1[C:19]2[C@@H:18]3[C@@H:9]([C@H:10]4[C@@:14]([CH2:16][CH2:17]3)([CH3:15])[C:13](=[O:20])[CH2:12][CH2:11]4)[CH2:8][CH2:7][C:6]=2[CH:5]=[C:4]([OH:21])[CH:3]=1.[N:22]1([S:28](Cl)(=[O:30])=[O:29])[CH2:27][CH2:26][CH2:25][CH2:24][CH2:23]1>>[N:22]1([S:28]([O:1][C:2]2[C:19]3[C@@H:18]4[C@@H:9]([C@H:10]5[C@@:14]([CH2:16][CH2:17]4)([CH3:15])[C:13](=[O:20])[CH2:12][CH2:11]5)[CH2:8][CH2:7][C:6]=3[CH:5]=[C:4]([O:21][S:28]([N:22]3[CH2:27][CH2:26][CH2:25][CH2:24][CH2:23]3)(=[O:30])=[O:29])[CH:3]=2)(=[O:30])=[O:29])[CH2:27][CH2:26][CH2:25][CH2:24][CH2:23]1

Participants

3

Reactant 2

HCID 11298344Piperidine-1-sulfonyl chlorideHCID 68148298HCID 68148298, compound

Product 1

HCID 68147447HCID 68147447, compound

Procedure

The above compound is prepared from 1,3-dihydroxy-8α-estra-1,3,5(10)-trien-17-one by reaction with piperidinosulfonyl chloride analogously to Example 24.

Sources & evidence

ORD record
ord-511e948f40704c918753ec7b75dc9641
Source dataset
uspto-grants-1976_04
Patent number
US03951959

Reaction notes

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