Sodium Hydroxide → 6,8-di-t-butyl-4-oxo-4H-1-benzopyran-2-carboxylic acid sodium salt

HRID 1606319Notes

Reaction equation

HRID 1606319 reaction equation
C([O:3][C:4]([C:6]1[O:7][C:8]2[C:16]([C:17]([CH3:20])([CH3:19])[CH3:18])=[CH:15][C:14]([C:21]([CH3:24])([CH3:23])[CH3:22])=[CH:13][C:9]=2[C:10](=[O:12])[CH:11]=1)=[O:5])C.[OH-].[Na+:26]>C(O)C>[Na+:26].[C:21]([C:14]1[CH:15]=[C:16]([C:17]([CH3:20])([CH3:19])[CH3:18])[C:8]2[O:7][C:6]([C:4]([O-:5])=[O:3])=[CH:11][C:10](=[O:12])[C:9]=2[CH:13]=1)([CH3:24])([CH3:23])[CH3:22]

Participants

4

Reactant 2

HCID 14798Sodium HydroxideHCID 538439426,8-di-t-butyl-4-oxo-4H-1-benzopyran-2-carboxylic acid, ethyl ester

Product 1

HCID 1317101456,8-di-t-butyl-4-oxo-4H-1-benzopyran-2-carboxylic acid sodium salt

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

To a chilled solution of 1.02 parts of 6,8-di-t-butyl-4-oxo-4H-1-benzopyran-2-carboxylic acid ethyl ester in 100 parts of ethanol was added 3.1 parts of N sodium hydroxide solution. After the solution had been stirred at room temperature for one hour the solvent was evaporated and the remaining solid was triturated with ether and filtered off to yield 0.93 parts of 6,8-di-t-butyl-4-oxo-4H-1-benzopyran-2-carboxylic acid sodium salt.

Workup

  1. customwas evaporated
  2. customthe remaining solid was triturated with ether
  3. filtrationfiltered off

Sources & evidence

ORD record
ord-68255df0168341b7bd82f859b17997ec
Source dataset
uspto-grants-1976_04
Patent number
US03952104

Reaction notes

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