m-Chloroperbenzoic acid → HCID 86733293, compound

Participants

Reaction Steps

To a solution of 5α-pregna- 2,16 -diene-11,20-dione (2.5 g.) in chloroform (50 ml.) was added m-chloroperoxybenzoic acid (85%, 1.8 g.), and the mixture was stirred at room temperature overnight. More chloroform was then added, and the solution was washed with dilute sodium bicarbonate solution and with water, dried over magnesium sulphate and evaporated to an oil which was triturated with ether/petrol to give title compound (1.9 g.) as colourless needles, m.p. 154°-156° , [α]D + 100°.

Provenance & Evidence