Pyridine → N-(2,4,6-tribromobenzoyl)-3,4-dibromohexahydrophthalimide

HRID 1606404Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1606404
[Br:1][CH:2]1[CH:12]([Br:13])[CH2:11][CH2:10][CH:4]2[C:5]([NH:7][C:8](=[O:9])[CH:3]12)=[O:6].N1C=CC=CC=1.[Br:20][C:21]1[CH:29]=[C:28]([Br:30])[CH:27]=[C:26]([Br:31])[C:22]=1[C:23](Cl)=[O:24]>C1C=CC=CC=1>[Br:20][C:21]1[CH:29]=[C:28]([Br:30])[CH:27]=[C:26]([Br:31])[C:22]=1[C:23]([N:7]1[C:8](=[O:9])[CH:3]2[CH:2]([Br:1])[CH:12]([Br:13])[CH2:11][CH2:10][CH:4]2[C:5]1=[O:6])=[O:24]

Komponenten

5

Edukt 3

HCID 1049PyridineHCID 11234266HCID 11234266, VerbindungHCID 215427963,4-Dibromohexahydrophthalimide

Produkt 1

HCID 21542800N-(2,4,6-tribromobenzoyl)-3,4-dibromohexahydrophthalimide

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 241BenzeneLösungsmittel

Versuchsvorschrift

3,4-Dibromohexahydrophthalimide (0.10 mole), benzene (300 ml) and pyridine (0.11 mole) are charged into a glass reaction vessel equipped with a mechanical stirrer, thermometer and reflux condenser. 2,4,6-Tribromobenzoyl chloride (0.10 mole) is then added dropwise to the flask with stirring at room temperature. After the addition is completed the reaction mixture is heated at reflux with continued stirring for a period of about 1 hour. After this time the reaction mixture is filtered and the filtrate is washed with water. The washed filtrate is then dried over anhydrous magnesium sulfate, filtered ans stripped of solvent under reduced pressure to yield the desired product N-(2,4,6-tribromobenzoyl)-3,4-dibromohexahydrophthalimide.

Aufarbeitung

  1. customequipped with a mechanical stirrer
  2. temperaturethermometer and reflux condenser
  3. additionAfter the addition
  4. temperatureis heated
  5. temperatureat reflux
  6. stirringwith continued stirring for a period of about 1 hour
  7. filtrationAfter this time the reaction mixture is filtered
  8. washthe filtrate is washed with water
  9. dry with materialThe washed filtrate is then dried over anhydrous magnesium sulfate
  10. filtrationfiltered ans

Quellen und Nachweise

ORD-Eintrag
ord-f33b8bfbee8b4bce8cc143e67b2fe5ac
Quelldatensatz
uspto-grants-1976_04
Patentnummer
US03953397

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