Pyridine → HCID 12521649, compound

Participants

Reaction Steps

To a suspension of 0.40 g. of 1,3,4,9-tetrahydro-4,6,7-trimethyl-10H-thieno[3,4-b] [1,5]benzodiazepin-10-one in 3 ml. of dry pyridine is added, in portions, a total of 0.21 g. of N-chlorosuccinimide. The resulting solution is heated on a steam bath for 15 minutes, cooled and diluted with water. The solid which separates is collected and recrystallized from methanol to give yellow crystals, m.p. 260°-262°C.

Provenance & Evidence