HCID 21543509, compound → HCID 178430965, compound

HRID 1606510Notes

Reaction equation

HRID 1606510 reaction equation
O[N:2]([OH:10])[C:3]([CH3:9])([C:5]([CH3:8])([NH2:7])[CH3:6])[CH3:4].I([O-])(=O)(=O)=[O:12].[Na+].C(Cl)(Cl)Cl.CO>O>[CH3:4][C:3]1([CH3:9])[C:5]([CH3:8])([CH3:6])[N+:7]([O-:12])=[N+:2]1[O-:10]

Participants

5

Reactant 3

HCID 21543509HCID 21543509, compoundHCID 21584188Chloroform methanolHCID 23667635Sodium periodate

Product 1

HCID 178430965HCID 178430965, compound

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

The product could also be obtained by oxidation of the dihydroxylamino precursor with sodium periodate. Thus, N,N-dihydroxy 2,3-dimethyl-2,3-diaminobutane (1.5 g) in water (50 ml) was stirred for 30 min. with aqueous sodium periodate (4.5 g in ca. 100 ml water). The product precipitated out and was washed with water, dried (MgSO4), and evaporated to give the product (800 mg. 65°) T.L.C. (silica, CHCl3 /MeOH;4/1) one spot, Rf 0.8

Workup

  1. customThe product precipitated out
  2. washwas washed with water
  3. dry with materialdried (MgSO4)
  4. customevaporated
  5. customto give the product (800 mg. 65°) T.L.C

Sources & evidence

ORD record
ord-cab88d76cdd945bca637ad60d9ad48b5
Source dataset
uspto-grants-1976_04
Patent number
US03953444

Reaction notes

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