29476-22-0 → HCID 21543845, compound

HRID 1606575Notes

Reaction equation

HRID 1606575 reaction equation
[C:1]1([CH:7]2[CH2:13][C:12](=O)[NH:11][C:10]3[CH:15]=[CH:16][CH:17]=[CH:18][C:9]=3[O:8]2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.C1(C2CC(=O)NC3C=CC=CC=3S2)C=CC=CC=1.[ClH:37].[CH3:38][N:39]([CH3:63])[CH2:40][CH2:41][N:42]([CH3:62])[C:43](N1C2C=CC=CC=2SC(C2C=CC=CC=2)CC1)=[O:44]>>[ClH:37].[CH3:38][N:39]([CH3:63])[CH2:40][CH2:41][N:42]([CH3:62])[C:43]([N:11]1[C:10]2[CH:15]=[CH:16][CH:17]=[CH:18][C:9]=2[O:8][CH:7]([C:1]2[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=2)[CH2:13][CH2:12]1)=[O:44]

Participants

4

Reactant 3

HCID 38949029476-22-0HCID 21543856HCID 21543856, compoundHCID 131710162HCID 131710162, compound

Product 1

HCID 21543845HCID 21543845, compound

Procedure

By substituting an equivalent amount of 2,3-dihydro-2-phenyl-1,5-benzoxazepin-4-(5H)-one, m.p. 123°-125°, (prepared as described in Example 1 of U.S. patent application, Ser. No. 328,048, filed Dec. 4, 1963 now U.S. Pat. No. 3,309,361), for the 2,3-dihydro-2-phenyl-1,5-benzothiazepin-4-one in part (A) of Example 1, and carrying out the procedure of the Example, there is obtained N-(2-dimethylaminoethyl)-2,3,4,5-tetrahydro-N-methyl-2-phenyl-1,5-benzoxazepine-5-carboxamide hydrochloride

Workup

  1. custom(prepared

Sources & evidence

ORD record
ord-40a56220597e4c47a9d8cefb3bd540f3
Source dataset
uspto-grants-1976_04
Patent number
US03953469

Reaction notes

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