Sodium Carbonate → HCID 13066649, compound

HRID 1606638Notes

Reaction equation

HRID 1606638 reaction equation
C([O:4][C:5]1[CH:36]=[CH:35][CH:34]=[CH:33][C:6]=1[C:7]([NH:9][C:10]1[CH:19]=[C:18]([NH:20][C:21](=[O:32])[C:22]2[CH:27]=[CH:26][CH:25]=[CH:24][C:23]=2[O:28]C(=O)C)[CH:17]=[CH:16][C:11]=1[C:12]([O:14][CH3:15])=[O:13])=[O:8])(=O)C.C(=O)([O-])[O-].[Na+].[Na+]>>[C:7]([NH:9][C:10]1[CH:19]=[C:18]([NH:20][C:21](=[O:32])[C:22]2[C:23](=[CH:24][CH:25]=[CH:26][CH:27]=2)[OH:28])[CH:17]=[CH:16][C:11]=1[C:12]([O:14][CH3:15])=[O:13])(=[O:8])[C:6]1[C:5](=[CH:36][CH:35]=[CH:34][CH:33]=1)[OH:4]

Participants

3

Reactant 2

HCID 10340Sodium CarbonateHCID 13066646HCID 13066646, compound

Product 1

HCID 13066649HCID 13066649, compoundYield 82%

Procedure

By the procedure similar to that described in Example 4, methyl 2,4-bis(2'-acetoxybenzamido)-benzoate was hydrolized with the aid of sodium carbonate to obtain crystals. Recrystallization of the crystals from a mixture of acetone, dioxane and water gave methyl 2,4-bis(salicylamido)-benzoate having a melting point between 259° - 260°C. (Yield: 82%)

Workup

  1. customto obtain crystals
  2. customRecrystallization of the crystals
  3. additionfrom a mixture of acetone, dioxane and water

Sources & evidence

ORD record
ord-c4470be2bad0477bb1315c467997c092
Source dataset
uspto-grants-1976_04
Patent number
US03953496

Reaction notes

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