Sodium Carbonate → HCID 13066650, compound

HRID 1606641Notes

Reaction equation

HRID 1606641 reaction equation
C([O:4][C:5]1[CH:35]=[CH:34][CH:33]=[CH:32][C:6]=1[C:7]([NH:9][C:10]1[CH:11]=[C:12]([CH:16]=[C:17]([NH:19][C:20](=[O:31])[C:21]2[CH:26]=[CH:25][CH:24]=[CH:23][C:22]=2[O:27]C(=O)C)[CH:18]=1)[C:13]([NH2:15])=[O:14])=[O:8])(=O)C.C(=O)([O-])[O-].[Na+].[Na+]>>[C:7]([NH:9][C:10]1[CH:11]=[C:12]([CH:16]=[C:17]([NH:19][C:20](=[O:31])[C:21]2[C:22](=[CH:23][CH:24]=[CH:25][CH:26]=2)[OH:27])[CH:18]=1)[C:13]([NH2:15])=[O:14])(=[O:8])[C:6]1[C:5](=[CH:35][CH:34]=[CH:33][CH:32]=1)[OH:4]

Participants

3

Reactant 2

HCID 10340Sodium CarbonateHCID 13066653HCID 13066653, compound

Product 1

HCID 13066650HCID 13066650, compoundYield 83%

Procedure

In the manner similar to that described in Example 4, 3,5-bis(2'-acetoxybenzamido)-benzamide obtained in Example 12 was hydrolyzed with sodium carbonate. Recrystallization of the hydrolized product from a mixture of ethanol and water gave 3,5-bis(salicylamido)-benzamide having a melting point between 276° - 277°C. (Yield; 83%)

Workup

  1. customRecrystallization of the hydrolized product
  2. additionfrom a mixture of ethanol and water

Sources & evidence

ORD record
ord-586987a062e349e79ea743c85e1e4861
Source dataset
uspto-grants-1976_04
Patent number
US03953496

Reaction notes

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