2-Ethoxybenzoyl chloride → HCID 21544122, compound

HRID 1606654Notes

Reaction equation

HRID 1606654 reaction equation
[NH2:1][C:2]1[CH:11]=[C:10]([NH:12][C:13](=[O:23])[C:14]2[CH:19]=[CH:18][CH:17]=[CH:16][C:15]=2[O:20][CH2:21][CH3:22])[CH:9]=[CH:8][C:3]=1[C:4]([O:6][CH3:7])=[O:5].[CH2:24]([O:26][C:27]1[CH:35]=[CH:34][CH:33]=[CH:32][C:28]=1[C:29](Cl)=[O:30])[CH3:25]>>[CH2:24]([O:26][C:27]1[CH:35]=[CH:34][CH:33]=[CH:32][C:28]=1[C:29]([NH:1][C:2]1[CH:11]=[C:10]([NH:12][C:13](=[O:23])[C:14]2[CH:19]=[CH:18][CH:17]=[CH:16][C:15]=2[O:20][CH2:21][CH3:22])[CH:9]=[CH:8][C:3]=1[C:4]([O:6][CH3:7])=[O:5])=[O:30])[CH3:25]

Participants

3

Reactant 2

HCID 30163972-Ethoxybenzoyl chlorideHCID 21544127HCID 21544127, compound

Product 1

HCID 21544122HCID 21544122, compound

Procedure

By the procedure similar to that described in Example 21, methyl 2-amino-4-(2'-ethoxybenzamido)-benzoate and 2-ethoxybenzoylchloride were reacted and treated to obtain crystals. Recrystallization from acetone gave methyl 2,4-bis(2'-ethoxybenzamido)-benzoate having a melting point between 199° - 200°C.

Workup

  1. customwere reacted
  2. additiontreated
  3. customto obtain crystals
  4. customRecrystallization from acetone

Sources & evidence

ORD record
ord-233c99e6139c4e3780086a28876b5b02
Source dataset
uspto-grants-1976_04
Patent number
US03953496

Reaction notes

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