Methoxyacetyl chloride → HCID 21427242, compound

HRID 1606671Notes

Reaction equation

[CH3:1][NH:2][C:3](=[O:28])[C@H:4]([CH2:21]C1C=CC=CC=1)[NH:5][C:6](=[O:20])[C:7]1[C:12]([I:13])=[C:11]([NH2:14])[C:10]([I:15])=[C:9]([C:16]([OH:18])=[O:17])[C:8]=1[I:19].[CH3:29][O:30][CH2:31][C:32](Cl)=[O:33]>>[CH3:1][NH:2][C:3](=[O:28])[CH:4]([CH3:21])[NH:5][C:6](=[O:20])[C:7]1[C:12]([I:13])=[C:11]([NH:14][C:32](=[O:33])[CH2:31][O:30][CH3:29])[C:10]([I:15])=[C:9]([C:16]([OH:18])=[O:17])[C:8]=1[I:19]

Participants

Reactant 2

HCID 96623Methoxyacetyl chloride

HCID 54110808HCID 54110808, compound

Product 1

HCID 21427242HCID 21427242, compound

Procedure

This compound is obtained as described in Example 11 from N-(3-carboxy-5-amino-2,4,6-triiodobenzoyl)-DL-alanine methylamide (IV d), m.p. 208°-209° C. (under decomposition), and methoxyacetyl chloride.

Workup

customThis compound is obtained

Sources & evidence

ORD record: ord-01a5e8eac2e54b94b3391f5aa1844459
Source dataset: uspto-grants-1976_04
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US03953501

Reaction notes

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