HCID 21409396, compound → 1-[4-(1-Hydroxy-2,2-dimethylpropyl)phenyl]propan-1-one

HRID 1606712Notes

Reaction equation

HRID 1606712 reaction equation
CC1(C2C=CC(C(O)C(C)(C)C)=CC=2)OCCO1.CC1(C2C=CC(C(O)C(C)(C)C)=CC=2Cl)OCCO1.[CH2:38]([C:40]1([C:45]2[CH:50]=[CH:49][C:48]([CH:51]([OH:56])[C:52]([CH3:55])([CH3:54])[CH3:53])=[CH:47][CH:46]=2)OCC[O:41]1)[CH3:39]>>[C:40]([C:45]1[CH:50]=[CH:49][C:48]([CH:51]([OH:56])[C:52]([CH3:55])([CH3:54])[CH3:53])=[CH:47][CH:46]=1)(=[O:41])[CH2:38][CH3:39]

Participants

4

Reactant 3

HCID 21409396HCID 21409396, compoundHCID 21409402HCID 21409402, compoundHCID 21409415HCID 21409415, compound

Product 1

HCID 214094141-[4-(1-Hydroxy-2,2-dimethylpropyl)phenyl]propan-1-one

Procedure

When the above reaction is carried out using in place of 2-methyl-2-(4-[1-hydroxy-2,2-dimethylpropyl]-phenyl)1,3-dioxolane, and equivalent amount of 2-methyl-2-(2-chloro-4-[1-hydroxy-2,2-dimethylpropyl]-phenyl)-1,3-dioxolane, or 2-ethyl-2 -(4-[1-hydroxy-2,2-dimethylpropyl]-phenyl)-1,3-dioxolane, there is obtained 1-(2-chloro-p-acetophenyl)-2,2-dimethylpropanol or 1-(p-propionylphenyl)-2,2-dimethylpropanol.

Workup

  1. customWhen the above reaction

Sources & evidence

ORD record
ord-2984150666a74f8bafe4818861fa7a82
Source dataset
uspto-grants-1976_04
Patent number
US03953525

Reaction notes

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