4-Methoxy-3-(trifluoromethyl)benzoic acid → 2-Methoxy-5-(trifluoromethyl)benzoic acid
Reaction equation
CO[C:3]1[C:11]([C:12]([F:15])([F:14])[F:13])=[CH:10][CH:9]=[CH:8][C:4]=1[C:5]([OH:7])=[O:6].FC(F)(F)C1C=C(C=CC=1OC)[C:21](O)=[O:22]>>[CH3:21][O:22][C:8]1[CH:9]=[CH:10][C:11]([C:12]([F:13])([F:14])[F:15])=[CH:3][C:4]=1[C:5]([OH:7])=[O:6]Participants
3
Procedure
In a similar manner are prepared 2-methoxy-3-trifluoromethylbenzoic acid and 3-trifluoromethyl-4-methoxybenzoic acid.
Sources & evidence
- ORD record
- ord-4e09ae22033b47c4a82f4b5bd05a4628
- Source dataset
- uspto-grants-1976_04
- Patent number
- US03953595
Reaction notes
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