Sodium Hydroxide → HCID 68126476, compound

HRID 1606766Notes

Reaction equation

HRID 1606766 reaction equation
[OH-].[Na+:2].[CH2:3]([O:10][C:11]1[CH:19]=[CH:18][C:17]([C:20]([F:23])([F:22])[F:21])=[CH:16][C:12]=1[C:13]([OH:15])=[O:14])[C:4]1[CH:9]=[CH:8][CH:7]=[CH:6][CH:5]=1>O>[Na+:2].[CH2:3]([O:10][C:11]1[CH:19]=[CH:18][C:17]([C:20]([F:21])([F:22])[F:23])=[CH:16][C:12]=1[C:13]([O-:15])=[O:14])[C:4]1[CH:5]=[CH:6][CH:7]=[CH:8][CH:9]=1

Participants

4

Reactant 2

HCID 14798Sodium HydroxideHCID 130269182-(Benzyloxy)-5-(trifluoromethyl)benzoic acid

Product 1

HCID 68126476HCID 68126476, compound

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

To a solution of 400 mg. (0.01 mole) of sodium hydroxide in 30 ml. of water is added, in portions and with stirring, 2.96 g. (0.01 mole) of 2-benzyloxy-5-trifluoromethylbenzoic acid. The slightly hazy solution is filtered and the filtrate concentrated at room temperature and under reduced pressure to dryness. The residual sodium salt is triturated with acetone and filtered.

Workup

  1. filtrationThe slightly hazy solution is filtered
  2. concentrationthe filtrate concentrated at room temperature and under reduced pressure to dryness
  3. customThe residual sodium salt is triturated with acetone
  4. filtrationfiltered

Sources & evidence

ORD record
ord-57459a4307384508a02b25e8bdfb35f7
Source dataset
uspto-grants-1976_04
Patent number
US03953595

Reaction notes

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