Phthalic Anhydride → HCID 21544573, compound

HRID 1606778Notes

Reaction equation

HRID 1606778 reaction equation
[CH:1]12[O:8][CH:5]([CH2:6][CH2:7]1)[CH2:4][NH:3][CH2:2]2.[C:9]1(=[O:19])[O:14][C:12](=[O:13])[C:11]2=[CH:15][CH:16]=[CH:17][CH:18]=[C:10]12>C1C=CC=CC=1>[C:12]([C:11]1[CH:15]=[CH:16][CH:17]=[CH:18][C:10]=1[C:9]([N:3]1[CH2:2][CH:1]2[O:8][CH:5]([CH2:6][CH2:7]2)[CH2:4]1)=[O:19])([OH:14])=[O:13]

Participants

4

Reactant 2

HCID 6811Phthalic AnhydrideHCID 120692318-Oxa-3-azabicyclo[3.2.1]octane

Product 1

HCID 21544573HCID 21544573, compound

Reagents, catalysts & solvents 1

HCID 241BenzeneSolvent2×

Procedure

A solution of 11.3 grams (0.1 mole) 8-oxa-3-azabicyclo (3.2.1)octane in 20 ml of benzene was added to a suspension of 14.8 grams (0.1 mole) of phthalic anhydride in 50 ml of benzene at 8° C. The reaction mixture was stirred for 1 hour and then left overnight at room temperature. The product, 20.0 grams which separated, was filtered off and recrystallized from benzene ethanol. The product represented by formula (X) had a melting point of 149°-150.5° C.

Workup

  1. waitleft overnight at room temperature
  2. customThe product, 20.0 grams which separated
  3. filtrationwas filtered off
  4. customrecrystallized from benzene ethanol

Sources & evidence

ORD record
ord-9fe9fbd11ee34de787a67fa9aa9460ff
Source dataset
uspto-grants-1976_04
Patent number
US03953596

Reaction notes

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