HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethyl isocyanate → 1-Ethyl-3-(1,2,3,4-tetrahydro-1-naphthyl)urea
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethyl isocyanate | HCID 8022 | — |
| Reactant | 1,2,3,4-Tetrahydro-1-naphthylamine | HCID 18066 | — |
| Solvent | Diethyl Ether | HCID 3283 | — |
| Product | 1-Ethyl-3-(1,2,3,4-tetrahydro-1-naphthyl)urea | HCID 21393476 | — |
Reaction Steps
A sample of 1,2,3,4-tetrahydro-1-naphthylamine (7.4 grams, 0.05 mole) is dissolved in 140 ml of ether and treated with a solution of ethyl isocyanate (3.6 grams, 0.05 mole) in 10 ml of ether. The reaction mixture is stirred at reflux for 3 hours, and then overnight at room temperature. The crude product is collected by filtration and recrystallized from a hot mixture of methanol and water. The yield is 7.8 grams (71.6%), melting point 178°C. to 179°C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US03953606 |
| Source dataset | uspto-grants-1976_04 |
| ORD ID | ord-effb22a9d83d4313aa4067dd3c7c4367 |
| Source note | uspto-grants-1976_04 |