HCID 131710175, compound → HCID 131710174, compound

Participants

Reaction Steps

A solution of 10.5 g. (14.5 mmoles) of Z-29-32-OtBu in 130 ml. of methanol is hydrogenated in the presence of 1 g. of palladium-on-carbon. When the reaction terminates, the catalyst is removed by filtration, and the filtrate is evaporated to dryness. The residue is triturated with petroleum ether. 8.35 g. (97.5 %) of H-29-32-OtBu are obtained. M.p.: 81-82°C; Rf11 = 0.1; [α]D = -24.3° (c = 1, in ethanol).

Provenance & Evidence