HCID 131710177, compound → HCID 131710176, compound

Participants

Reaction Steps

A solution of 8.0 g. (8.8 mmoles) of Z-28-32-OtBu in 160 ml. of methanol is hydrogenated in the presence of 1 g. of palladium-on-carbon. When the reaction terminates, the catalyst is filtered off, the filtrate is evaporated to dryness, and the residue is triturated with ether and petroleum ether. 6.4 g. (94 %) of H-28-32-OtBu are obtained. M.p.: 138-139°C; Rf12 = 0.1; [α]D = -9.7° (c = 1, in ethanol).

Provenance & Evidence