HCID 131710185, compound → HCID 131710184, compound

Participants

Reaction Steps

78.95 g. (60.15 mmoles) of Z-31-39-OtBu are dissolved in 1500 ml. of 80 % acetic acid, and the mixture is hydrogenated in the presence of palladium-on-carbon. When the reaction terminates, the catalyst is filtered off, and the filtrate is evaporated to dryness. The residue is triturated with ether and filtered. 74.35 g. (99 %) of H-31-39-OtBu are obtained. M.p.: 105°C (under decomposition), Rf7 = 0.5.

Provenance & Evidence