HCID 131710187, compound → HCID 131710186, compound

Participants

Reaction Steps

67.25 g. (42.15 mmoles) of Z-29-39-OtBu are dissolved in 1300 ml. of 80 % acetic acid, and the mixture is hydrogenated in the presence of palladium-on-carbon. At the end of the reaction the catalyst is filtered off, and the filtrate is evaporated to dryness. The residue is triturated with ether, the solid is filtered off, and dried. 63.8 g. (95%) of H-29-39OtBu are obtained. M.p.: 128°-132° C (under decomposition), Rf5 = 0.3.

Provenance & Evidence