HCID 131710189, compound → HCID 131710188, compound

Participants

Reaction Steps

8.5 g. 4.41 mmoles) of Z-27-39-OtBu are dissolved in 850 ml. of dry DMF, and the mixture is hydrogenated in the presence of palladium-on-carbon. At the end of the reaction, the catalyst is removed by filtration; the filtate is evaporated to dryness, and the residue is triturated with ether. 7.65 g. (96.9 %) of H-27-39-OtBu are obtained. M.p.: 197°C (under decomposition), Rf12 = 0.3.

Provenance & Evidence