O-((2E)-3-Chloro-2-propen-1-yl)hydroxylamine → 2-[(E)-N-(3-chloroprop-2-enoxy)-C-ethylcarbonimidoyl]-5-(2-methylpyrazol-3-yl)cyclohexane-1,3-dione

Participants

Reaction Steps

To 5 ml of an ethanolic solution of 0.35 g (1.4 mmols) of 5-(1-methyl-1H-pyrazol-5-yl)-2-propionylcyclohexane-1,3-dione was added 3.8 ml (1.4 mmols) of 0.38 mol ethanolic solution of (E)-3-chloro-2-propenyloxyamine. The mixture was reacted for 10 hours with stirring. After completion of the reaction, the reaction mixture was concentrated under reduced pressure. The resulting crude product was purified by silica gel column chromatography (hexane:ethyl acetate=b 1:2) to give 0.25 g of the product.

Provenance & Evidence