Isopropyl iodide → HCID 131716090, compound

HRID 1607069Notes

Reaction equation

[CH:1](I)([CH3:3])[CH3:2].Br[C:6]1[CH:7]=[C:8]2[C:21]3[C:11]([CH2:12][C@@H:13]4[C@@H:18]([C:19]=3[CH:20]=1)[CH2:17][C@H:16]([NH:22][C:23](=[O:29])[N:24]([CH2:27][CH3:28])[CH2:25][CH3:26])[CH2:15][N:14]4[CH2:30]CC)=[CH:10][N:9]2[Si](C(C)(C)C)(C)C>>[CH2:27]([N:24]([CH2:25][CH3:26])[C:23]([NH:22][C@H:16]1[CH2:17][C@H:18]2[C@@H:13]([CH2:12][C:11]3[C:21]4[C:8](=[CH:7][C:6]([CH:1]([CH3:3])[CH3:2])=[CH:20][C:19]2=4)[NH:9][CH:10]=3)[N:14]([CH3:30])[CH2:15]1)=[O:29])[CH3:28]

Participants

Reactant 2

HCID 6362Isopropyl iodide

HCID 131716089HCID 131716089, compound

Product 1

HCID 131716090HCID 131716090, compound

Procedure

With isopropyl iodide and 3-(13-bromo-1-tert-butyldimethylsilyl-6-n-propyl-8α-ergolinyl)-1,1-diethylurea:

Sources & evidence

ORD record: ord-434856ed80994e569cf69511b9297b8c
Source dataset: uspto-grants-1989_09
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04863929

Reaction notes

Loading…