N-Iodosuccinimide → HCID 131716096, compound

HRID 1607075Notes

Reaction equation

[I:1]N1C(=O)CCC1=O.Br[C:10]1[C:24]2=[C:25]3[C:13]([N:14]([Si](C(C)(C)C)(C)C)[CH2:15][CH:16]3[CH2:17][C@@H:18]3[C@@H:23]2[CH2:22][C@H:21]([NH:26][C:27](=[O:33])[N:28]([CH2:31][CH3:32])[CH2:29][CH3:30])[CH2:20][N:19]3[CH3:34])=[CH:12][CH:11]=1>>[CH2:29]([N:28]([CH2:31][CH3:32])[C:27]([NH:26][C@H:21]1[CH2:22][C@H:23]2[C@@H:18]([CH2:17][C:16]3[C:25]4[C:13](=[CH:12][C:11]([I:1])=[CH:10][C:24]2=4)[NH:14][CH:15]=3)[N:19]([CH3:34])[CH2:20]1)=[O:33])[CH3:30]

Participants

Reactant 2

HCID 120273N-Iodosuccinimide

HCID 131716097HCID 131716097, compound

Product 1

HCID 131716096HCID 131716096, compound

Procedure

With N-iodosuccinimide and 3-(12-bromo-1-tert-butyldimethylsilyl-2,3-dihydro-6-methyl-8α-ergolinyl)-1,1diethylurea:

Sources & evidence

ORD record: ord-b3e1c02b7e384d68be33b992652fe220
Source dataset: uspto-grants-1989_09
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04863929

Reaction notes

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