Iodine → HCID 131716098, compound

HRID 1607076Notes

Reaction equation

[I:1]I.Br[C:4]1[CH:5]=[C:6]2[C:19]3[CH:9]([CH2:10][C@@H:11]4[C@@H:16]([C:17]=3[CH:18]=1)[CH2:15][C@H:14]([NH:20][C:21](=[O:27])[N:22]([CH2:25][CH3:26])[CH2:23][CH3:24])[CH2:13][N:12]4[CH3:28])[CH2:8][N:7]2[Si](C(C)(C)C)(C)C>>[CH2:23]([N:22]([CH2:25][CH3:26])[C:21]([NH:20][C@H:14]1[CH2:15][C@H:16]2[C@@H:11]([CH2:10][CH:9]3[C:19]4[C:6](=[CH:5][CH:4]=[C:18]([I:1])[C:17]2=4)[NH:7][CH2:8]3)[N:12]([CH3:28])[CH2:13]1)=[O:27])[CH3:24]

Participants

Reactant 2

HCID 807Iodine

HCID 131716087HCID 131716087, compound

Product 1

HCID 131716098HCID 131716098, compound

Procedure

With iodine and 3-(13-bromo-1-tert-butyldimethylsilyl2,3-dihydro-6-methyl-8α-ergolinyl)-1,1-diethylurea:

Sources & evidence

ORD record: ord-e96f9fab0c8a4d09bb6914fb0bca6529
Source dataset: uspto-grants-1989_09
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04863929

Reaction notes

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