Iodine → HCID 131716099, compound

HRID 1607077Notes

Reaction equation

[I:1]I.Br[C:4]1[C:18]2=[C:19]3[C:7]([N:8]([Si](C(C)(C)C)(C)C)[CH:9]=[C:10]3[CH2:11][C@@H:12]3[C:17]2=[CH:16][C@H:15]([NH:20][C:21](=[O:27])[N:22]([CH2:25][CH3:26])[CH2:23][CH3:24])[CH2:14][N:13]3[CH3:28])=[CH:6][CH:5]=1>>[CH2:23]([N:22]([CH2:25][CH3:26])[C:21]([NH:20][C@H:15]1[CH2:16][C@H:17]2[C@@H:12]([CH2:11][CH:10]3[C:19]4[C:7](=[CH:6][C:5]([I:1])=[CH:4][C:18]2=4)[NH:8][CH2:9]3)[N:13]([CH3:28])[CH2:14]1)=[O:27])[CH3:24]

Participants

Reactant 2

HCID 807Iodine

HCID 131716094HCID 131716094, compound

Product 1

HCID 131716099HCID 131716099, compound

Procedure

With iodine and 3-(12-bromo-1-tert-butyldimethylsilyl9,10-didehydro-6-methyl-8α-ergolinyl)-1,1-diethylurea:

Sources & evidence

ORD record: ord-708250fa03034165842f3f8fc1bf64c5
Source dataset: uspto-grants-1989_09
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04863929

Reaction notes

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